Churg-Strauss Syndrome (CSS), also called Eosinophilic Granulomatosis with Polyangiitis (EGPA), is a rare autoimmune disease that predominantly affects the blood vessels, leading to widespread inflammation. While this vasculitis can target many organs in the body, the lungs are particularly vulnerable. Respiratory symptoms are often the first indicators of the disease and can be one of its most challenging aspects. In fact, many patients first present with symptoms that resemble asthma or other...
Churg-Strauss Syndrome (CSS), now known as Eosinophilic Granulomatosis with Polyangiitis (EGPA), is a rare autoimmune disease that affects the blood vessels and multiple organ systems. Like many autoimmune diseases, the root of CSS lies in a malfunction of the immune system. Understanding the intricate relationship between CSS and the immune system is key to understanding the disease itself - how it manifests, how it progresses, and how it is treated.
The immune system is responsible for defend...
Eosinophils are a crucial component in understanding Churg-Strauss Syndrome (CSS), also known as Eosinophilic Granulomatosis with Polyangiitis (EGPA). These white blood cells, typically associated with allergic reactions and the immune response to parasites, play a central role in the disease. In CSS/EGPA, eosinophils are overproduced and accumulate in tissues, leading to inflammation, damage, and a wide range of symptoms.
To understand the role of eosinophils in CSS, it's essential to explore...
If you've been researching Churg-Strauss Syndrome (CSS), you may have come across another term: Eosinophilic Granulomatosis with Polyangiitis (EGPA). You might wonder: are they the same condition? The short answer is yes, but it's a bit more complex than that. Over the years, the name for this disease has evolved, and understanding why can give you a clearer picture of what CSS, or EGPA, actually entails.
Churg-Strauss Syndrome was first described...
Churg-Strauss Syndrome (CSS), also known as Eosinophilic Granulomatosis with Polyangiitis (EGPA), is a rare form of vasculitis - a disease that causes inflammation of the blood vessels. The hallmark of CSS is the abnormal accumulation of eosinophils, a type of white blood cell associated with allergic reactions and asthma. These eosinophils can invade various organs and tissues, leading to a wide range of symptoms, some of which can be life-threatening.
The impact of Churg-Strauss Syndrome on t...
Churg-Strauss Syndrome (CSS), also known as Eosinophilic Granulomatosis with Polyangiitis (EGPA), is a complex autoimmune disease that primarily affects small- and medium-sized blood vessels. Although it is a rare condition, understanding what causes it is crucial in grasping the mechanisms behind the disease and its treatment.
Unlike some diseases where the causes are clear, CSS does not have a straightforward or well-understood origin. However, current research points to a combination of gene...