Living with Churg-Strauss Syndrome (CSS), or Eosinophilic Granulomatosis with Polyangiitis (EGPA), involves cycles of remission and flare-ups. During remission, the symptoms may be under control with medication, and you might feel like your normal self. But a flare-up can bring a sudden return of the symptoms, often more severe than before. These flare-ups are unpredictable, but they are part of managing the disease.

While every individual's experience can be different, there are common sig...

Churg-Strauss Syndrome (CSS), also known as Eosinophilic Granulomatosis with Polyangiitis (EGPA), is a rare autoimmune disorder characterized by inflammation of blood vessels (vasculitis), which can affect multiple organ systems, including the lungs, skin, heart, and nerves. The condition is typically progressive, and its early symptoms may mimic more common illnesses like asthma or allergies, making early diagnosis challenging. Identifying the signs of CSS at its earliest stages is crucial for...

Living with Churg-Strauss Syndrome (CSS), or Eosinophilic Granulomatosis with Polyangiitis (EGPA), is a journey that often begins with confusion, misdiagnosis, and frustration. Since CSS is a rare condition, patients may spend years trying to pinpoint the root cause of their symptoms. For many, their lives are disrupted by recurring health issues like asthma, allergies, and unexplained fatigue long before they receive the proper diagnosis.

The following is a hypothetical patient's story. This n...

Churg-Strauss Syndrome (CSS), also called Eosinophilic Granulomatosis with Polyangiitis (EGPA), is a rare autoimmune disease that predominantly affects the blood vessels, leading to widespread inflammation. While this vasculitis can target many organs in the body, the lungs are particularly vulnerable. Respiratory symptoms are often the first indicators of the disease and can be one of its most challenging aspects. In fact, many patients first present with symptoms that resemble asthma or other...

Churg-Strauss Syndrome (CSS), now known as Eosinophilic Granulomatosis with Polyangiitis (EGPA), is a rare autoimmune disease that affects the blood vessels and multiple organ systems. Like many autoimmune diseases, the root of CSS lies in a malfunction of the immune system. Understanding the intricate relationship between CSS and the immune system is key to understanding the disease itself - how it manifests, how it progresses, and how it is treated.

The immune system is responsible for defend...

Eosinophils are a crucial component in understanding Churg-Strauss Syndrome (CSS), also known as Eosinophilic Granulomatosis with Polyangiitis (EGPA). These white blood cells, typically associated with allergic reactions and the immune response to parasites, play a central role in the disease. In CSS/EGPA, eosinophils are overproduced and accumulate in tissues, leading to inflammation, damage, and a wide range of symptoms.

To understand the role of eosinophils in CSS, it's essential to explore...